Clinical Research Trials and Studies
These aid in finding treatments and cures for various visual conditions and diseases. Clinical research can be funded either through private or government entities. All clinical research supported by the National Eye Institute is conducted through our Vision Research Laboratories.
The New England Eye Center also participates in corporate or privately sponsored clinical trials that are administered through its various specialties.
Contact Information:
The following clinical trials are currently taking place at:
Tufts Medical Center
New England Eye Center
800 Washington Street
Boston, MA 02111
For more details about any of these studies, or, to participate, please call one of the following people:
- Beverly Snell – Clinical Research Coordinator, 617-636-5489
- Julie S. Burt, Clinical Research Assistant III, 617-636-0747
AGE-RELATED MACULAR DEGENERATION (AMD)
EPI-RAD90™ Ophthalmic System vs. Lucentis®
Target Population: Males and females, 50 years and older, with newly diagnosed or untreated AMD
Study Duration: 3 years
Description: The purpose of this study is to determine whether an investigational device, called Epi-Rad90™ Ophthalmic System, is effective and safe for use in wet age-related macular degeneration. Subjects will receive either a dose of radiation to their eye from the Epi-Rad plus a drug called Lucentis® or they will receive eye injections of Lucentis® only. Lucentis® is a FDA approved drug for the treatment of AMD.Etiologic Studies of Age Related Macular Degeneration
Target Population: Individuals with advanced stages of macular degeneration (wet or dry) over age 55
Study Duration :On-going
Description: The purpose of this research study is to determine the causes of macular degeneration so we can prevent it and find better treatments. We will identify genes and environmental determinants of AMD. Eligible study participants will have an eye exam and blood draw. Participants will also complete questionnaires on diet and risk factors.YOU DO NOT NEED TO LIVE IN THE BOSTON AREA TO PARTICIPATE.
Please call us at: 1-800-219-9157 for more information.
DIABETIC MACULAR EDEMA (DME)
PF-04523655 vs. LASER
Target Population: Males and females, 18 years and older, with DME
Study Duration: 3 years
Description: The purpose of this study is to evaluate the safety and effectiveness of an investigational drug, known as PF-04523655, for use in diabetic macular edema. Subjects will either receive 1 of 3 doses of the study drug or they will receive laser treatment to their eye. PF-04523655 is given as an eye injection.

