Dry Eye Disease (DED)

Primary Investigator: Pedram Hamrah, MD

Title: The utility of in vivo confocal microscopy to assess cellular response and efficacy of long-term topical steroid treatment in patients with dry eye disease

Sponsor: GlaxoSmithKline plc

Inclusion Criteria
Symptoms of DED for at least 6 months, 2 or more of the following: Schirmer test <10mm at 5 minutes, TBUT <10 seconds, Corneal fluorescein staining of 4 (NEI grading) in at least one eye, Lissamine green staining of nasal & temporal conjunctiva (NEI grading) in at least one eye, Corneal dendritiform cell count by confocal microscopy of >=75/mm2 

Study Length and Visits: 3 study visits over 6 week period

Age Range: 18-89 years

Payment: $50 per visit

Contact: Mildred Commodore, 617-636-1051 or Carly Satsuma, 617-636-5489