M. Reza Vagefi, M.D.

Dr. Vagefi is available for appointments in Boston.


Reza Vagefi, M.D. is Professor and Chair of the Department of Ophthalmology at Tufts University, School of Medicine. He is the Director of the New England Eye Center at Tufts Medical Center. 

Dr. Vagefi specializes in oculofacial plastic and orbital surgery. He is recognized in the field for his contributions to the treatment of orbital tumors and infections. He has developed new surgical methods for oculofacial plastic surgery and has trained over 100 medical students, residents, and clinical fellows. Dr. Vagefi is well published in peer reviewed journals and regularly presents at national and international meetings. 

Dr. Vagefi is acknowledged by national organizations as one of the top doctors in the United States in his subspecialty. He is a fellow of the American Academy of Ophthalmology (AAO) and member of the American Society of Ophthalmic Plastic & Reconstructive Surgery (ASOPRS). Dr. Vagefi has served on the Board of Directors for ASOPRS as the Director of Fellowship Education. He has also served on the AAO Basic and Clinical Science Course Committee and Ophthalmic Technology Assessment Committee. He has been recognized with a number of awards including an AAO Achievement Award and an ASOPRS Service Award.

Clinical Interest

Dr. Vagefi specializes in plastic and reconstructive surgery of the eyelids, tear drainage system, orbit, and face. He has a particular interest in skull-based tumors and complex orbital and adnexal reconstructions.

Research Interests

Dr. Vagefi’s research has focused on surgical and quality of life outcomes, patient specific implants for oculofacial reconstruction, metagenomics of orbital inflammatory disease, multidisciplinary approaches to the skull base, and diagnostic imaging and treatment of acute invasive fungal rhinosinusitis.


Oculofacial Plastic and Orbital Surgery; Center for Facial Appearances; Salt Lake City, UT


University of California, San Francisco; San Francisco, CA


Stanford University, School of Medicine; Palo Alto, CA

Medical School

Yale University, School of Medicine; New Haven , CT

Academic Appointment

Professor of Ophthalmology, Tufts University School of Medicine

Board Certification

American Board of Ophthalmology

Professional Honors and Awards

2006 – California Academy of Ophthalmology, Starr E. Shulman MPA Fellowship
2010 – University of Pennsylvania, Scheie Eye Institute, Surgical Teaching Award
2016 – American Academy of Ophthalmology, Achievement Award
2022 – University of California San Francisco, Exceptional Physician Award Honorable Mention
2022 – University of California San Francisco, School of Medicine, Michal Vilensky Endowed Chair for Research in Ophthalmology,
2023 – American Society of Ophthalmic Plastic & Reconstructive Surgery, Service Award

Academic Affiliations/Memberships

American Eye Study Club
American Medical Association
American Academy of Ophthalmology
American Society of Ophthalmic Plastic & Reconstructive Surgery
Association of University Professors of Ophthalmology
Frederick C. Cordes Eyes Society
Massachusetts Society of Eye Physicians and Surgeons

Selected Publications

Dr. Vagefi has over 120 peer-reviewed publications. Below are some select examples:

Vagefi MR, Idowu OO, Miller A, Doan T, Chen C, Hinterwirth A, Zhong L, Ahmad M, Ashraf DC, Grob SR, Kersten RC, Winn BJ. Metagenomic Deep Sequencing for Orbital Inflammatory Disease. Ocul Immunol Inflamm. 2023:1-4. 

Ashraf DC, Miller A, Ahmad M, Smith LD, Grob SR, Winn BJ, Kersten RC, Vagefi MR. Augmentation of telemedicine post-operative follow-up after oculofacial plastic surgery with a self-guided patient tool. Orbit. 2023;42:372-382.

Idowu OO, Soderlund KA, Laguna B, Ashraf DC, Arnold BF, Grob SR, Winn BJ, Russell MS, Kersten RC, Dillon WP, Vagefi MR. Magnetic Resonance Imaging Prognostic Findings for Visual and Mortality Outcomes in Acute Invasive Fungal Rhinosinusitis. Ophthalmology. 2022;129:1313-1322. 

Ashraf DC, Idowu OO, Hirabayashi KE, Kalin-Hajdu E, Grob SR, Winn BJ, Vagefi MR, Kersten RC. Outcomes of a Modified Treatment Ladder Algorithm Using Retrobulbar Amphotericin B for Invasive Fungal Rhino-Orbital Sinusitis. Am J Ophthalmol. 2022;237:299-309. 

Alsoudi AF, Ton L, Ashraf DC, Idowu OO, Kong AW, Wang L, Kersten RC, Winn BJ, Grob SR, Vagefi MR. Efficacy of Care and Antibiotic Use for Chalazia and Hordeola. Eye Contact Lens. 2022;48:162-168.

Kinde B, Idowu OO, Ashraf DC, Chen RM, Hirabayashi KE, Grob SR, Winn BJ, Kersten RC, Vagefi MR. Quality-of-Life Outcomes for Excision and Reconstruction of Periocular Nonmelanoma Skin Cancer. Facial Plast Surg Aesthet Med. 2021. Epub ahead of print. PMID: 34227877.

Copperman TS, Idowu OO, Jalaj S, Winn BJ, Pham C, Setabutr P, Kersten RC, Vagefi MR. Patient-Specific Implants in Oculofacial Plastic Surgery. Ophthalmic Plast Reconstr Surg. 2021;37:241-247. 

Idowu OO, Ashraf DC, Magill ST, Kersten RC, McDermott MW, Vagefi MR. Multidisciplinary Frontotemporal Orbitozygomatic Craniotomy for Spheno-orbital Meningiomas: Ophthalmic and Orbital Outcomes. Ophthalmic Plast Reconstr Surg. 2021;37:18-26.

Ashraf DC, Idowu OO, Wang Q, YeEun T, Copperman TS, Tanaboonyawat S, Arnold BF, Oldenburg CE, Vagefi MR, Kersten RC. The Role of Topical Antibiotic Prophylaxis in Oculofacial Plastic Surgery: A Randomized Controlled Study. Ophthalmology. 2020;127:1747-1754.

Hirabayashi KE, Idowu OO, Kalin-Hajdu E, Oldenburg CE, Brodie FL, Kersten RC, Vagefi MR. Invasive Fungal Sinusitis: Risk Factors for Visual Acuity Outcomes and Mortality. Ophthalmic Plast Reconstr Surg. 2019;35:535-542.

Grumbine FL, Idowu O, Kersten RC, Deparis SW, Vagefi MR. Correction of Lower Eyelid Retraction with En Glove Placement of Porcine Dermal Collagen Matrix Implant. Plast Reconstr Surg. 2019;143:743-746.

Contact Information

Dr. Vagefi’s Office: 617-636-9142

Fax: 617-636-4866

Patient Appointments: Boston: 617-636-4600

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